Additive Manufacturing (AM), often referred to as 3D printing, is a generic term describing the layered build-up of material in near net shape frequently attributed with a freedom of design that cannot be achieved otherwise. AM focuses basically on the fabrication of parts for different fields in complex high-tech applications. Examples include components for jet engines, turbines blades and implants in the medical sector. This is often justified with tool cost savings, shorter lead-time and overcoming the “Design for manufacture” paradigm. On the other hand, a machining allowance is frequently required to counteract the inherent surface roughness and the widespread challenge of part distortion due to residual stresses. At this point, geometrical complexity and small batch sizes transform into strong cost drivers compared to conventional subtractive processing. In fact, these parts are simply hard-to-clamp and hard-to-probe. Moreover, iterative processing is frequently required due to remaining residual stresses in order to reach the target geometry, even the part envelope changes unintentionally. The current paper explores the novel approach of semi-autonomous post-processing of AM parts and components based on flexible clamping, geometry acquisition in the as-clamped position using cooperating laser profile sensors and an adaptive milling path planning strategy to counteract unforeseen change of the part envelope.